[HTML][HTML] Fish oil increases raft size and membrane order of B cells accompanied by differential effects on function
BD Rockett, H Teague, M Harris, M Melton… - Journal of lipid …, 2012 - ASBMB
Fish oil (FO) targets lipid microdomain organization to suppress T-cell and macrophage
function; however, little is known about this relationship with B cells, especially at the animal
level. We previously established that a high FO dose diminished mouse B-cell lipid raft
microdomain clustering induced by cross-linking GM1. To establish relevance, here we
tested a FO dose modeling human intake on B-cell raft organization relative to a control.
Biochemical analysis revealed more docosahexaenoic acid (DHA) incorporated into …
function; however, little is known about this relationship with B cells, especially at the animal
level. We previously established that a high FO dose diminished mouse B-cell lipid raft
microdomain clustering induced by cross-linking GM1. To establish relevance, here we
tested a FO dose modeling human intake on B-cell raft organization relative to a control.
Biochemical analysis revealed more docosahexaenoic acid (DHA) incorporated into …