[HTML][HTML] Diversity and function of membrane glycerophospholipids generated by the remodeling pathway in mammalian cells
Cellular membranes are composed of numerous kinds of glycerophospholipids with different
combinations of polar heads at the sn-3 position and acyl moieties at the sn-1 and sn-2
positions, respectively. The glycerophospholipid compositions of different cell types,
organelles, and inner/outer plasma membrane leaflets are quite diverse. The acyl moieties
of glycerophospholipids synthesized in the de novo pathway are subsequently remodeled
by the action of phospholipases and lysophospholipid acyltransferases. This remodeling …
combinations of polar heads at the sn-3 position and acyl moieties at the sn-1 and sn-2
positions, respectively. The glycerophospholipid compositions of different cell types,
organelles, and inner/outer plasma membrane leaflets are quite diverse. The acyl moieties
of glycerophospholipids synthesized in the de novo pathway are subsequently remodeled
by the action of phospholipases and lysophospholipid acyltransferases. This remodeling …