Duchenne muscular dystrophy: survival by cardio-respiratory interventions
Y Ishikawa, T Miura, Y Ishikawa, T Aoyagi… - Neuromuscular …, 2011 - Elsevier
We describe survival in Duchenne dystrophy by invasive and noninvasive ventilation vs.
untreated. Patients were untreated prior to 1984 (Group 1), underwent tracheotomy from
1984 until 1991 (Group 2), and were managed by noninvasive mechanical ventilation and
cardioprotective medications subsequently (Group 3). Symptoms, vital capacity, and blood
gases were monitored for all and spirometry, cough peak flows, carbon dioxide tension, and
oximetry for Group 3. Sleep nasal ventilation was initiated for symptomatic hypoventilation …
untreated. Patients were untreated prior to 1984 (Group 1), underwent tracheotomy from
1984 until 1991 (Group 2), and were managed by noninvasive mechanical ventilation and
cardioprotective medications subsequently (Group 3). Symptoms, vital capacity, and blood
gases were monitored for all and spirometry, cough peak flows, carbon dioxide tension, and
oximetry for Group 3. Sleep nasal ventilation was initiated for symptomatic hypoventilation …