Peritumoral neutrophils link inflammatory response to disease progression by fostering angiogenesis in hepatocellular carcinoma
DM Kuang, Q Zhao, Y Wu, C Peng, J Wang, Z Xu… - Journal of …, 2011 - Elsevier
BACKGROUND & AIMS: Substantial evidence indicates that inflammation is a critical
component of tumor progression. Hepatocellular carcinoma (HCC) is usually derived from
inflamed cirrhotic liver with extensive leukocyte infiltration. Neutrophils are the common
inflammatory infiltrate in tumors, but their nature and regulation in human cancers remain
elusive. METHODS: A total of 238 HCC patients were enrolled randomly.
Immunohistochemistry and SuperArray Real-Time PCR were used to analyze the …
component of tumor progression. Hepatocellular carcinoma (HCC) is usually derived from
inflamed cirrhotic liver with extensive leukocyte infiltration. Neutrophils are the common
inflammatory infiltrate in tumors, but their nature and regulation in human cancers remain
elusive. METHODS: A total of 238 HCC patients were enrolled randomly.
Immunohistochemistry and SuperArray Real-Time PCR were used to analyze the …