[HTML][HTML] Heterocyclic aromatic amine intake increases colorectal adenoma risk: findings from a prospective European cohort study

S Rohrmann, S Hermann, J Linseisen - The American journal of clinical …, 2009 - Elsevier
Abstract Background Heterocyclic aromatic amines (HCAs), which arise from cooking meat
and fish at high temperatures, may increase the risk of colorectal adenomas. Conversely,
flavonoids might counteract the negative effects of HCAs. Objective The association
between dietary HCA intake and colorectal adenoma incidence was investigated in a
prospective cohort study. Design: At recruitment (1994–1998), detailed information on diet,
anthropometric measures, lifestyle, and medication use was assessed in 25,540 participants …