Reduced hippocampal volume correlates with executive dysfunctioning in major depression

T Frodl, A Schaub, S Banac, M Charypar, M Jäger… - Journal of Psychiatry and …, 2006 - jpn.ca
Objective: Dysfunction of neuronal plasticity or remodelling seems to contribute to the
pathopysiology of major depression and may cause the well-documented hippocampal
changes in depression. We aimed to investigate whether reduced hippocampal volumes
correlate with executive dysfunctioning or memory dysfunctioning or with depression
severity. Methods: We recruited 34 inpatients with a previous or current episode of major
depression from the department of psychiatry at the Ludwig-Maximilians University of …