[PDF][PDF] Metagenomic approaches for defining the pathogenesis of inflammatory bowel diseases

DA Peterson, DN Frank, NR Pace, JI Gordon - Cell host & microbe, 2008 - cell.com
Cell host & microbe, 2008cell.com
The human gastrointestinal tract is home to immense and complex populations of
microorganisms. Using recent technical innovations, the diversity present in this human
body habitat is now being analyzed in detail. This review focuses on the microbial ecology of
the gut in inflammatory bowel diseases and on how recent studies provide an impetus for
using carefully designed, comparative metagenomic approaches to delve into the structure
and activities of the gut microbial community and its interrelationship with the immune …
Summary
The human gastrointestinal tract is home to immense and complex populations of microorganisms. Using recent technical innovations, the diversity present in this human body habitat is now being analyzed in detail. This review focuses on the microbial ecology of the gut in inflammatory bowel diseases and on how recent studies provide an impetus for using carefully designed, comparative metagenomic approaches to delve into the structure and activities of the gut microbial community and its interrelationship with the immune system.
cell.com