NMDA/glutamate mechanism of antidepressant-like action of magnesium in forced swim test in mice
E Poleszak, P Wlaź, E Kędzierska, D Nieoczym… - Pharmacology …, 2007 - Elsevier
Antidepressant-like activity of magnesium in forced swim test (FST) was demonstrated
previously. Also, enhancement of such activity by joint administration of magnesium and
antidepressants was shown. However, the mechanism (s) involved in such activity remain to
be established. In the present study we examined the involvement of NMDA/glutamate
pathway in the magnesium activity in FST in mice. In the present study we investigated the
effect of NMDA agonists on magnesium-induced activity in FST and the influence of NMDA …
previously. Also, enhancement of such activity by joint administration of magnesium and
antidepressants was shown. However, the mechanism (s) involved in such activity remain to
be established. In the present study we examined the involvement of NMDA/glutamate
pathway in the magnesium activity in FST in mice. In the present study we investigated the
effect of NMDA agonists on magnesium-induced activity in FST and the influence of NMDA …