[HTML][HTML] Cholesteryl ester transfer protein and phospholipid transfer protein have nonoverlapping functions in vivo
K Kawano, SC Qin, M Lin, AR Tall, X Jiang - Journal of Biological Chemistry, 2000 - ASBMB
Plasma phospholipid transfer protein (PLTP) and cholesteryl ester transfer protein (CETP)
are homologous molecules that mediate neutral lipid and phospholipid exchange between
plasma lipoproteins. Biochemical experiments suggest that only CETP can transfer neutral
lipids but that there could be overlap in the ability of PLTP and CETP to transfer or exchange
phospholipids. Recently developed PLTP gene knock-out (PLTP0) mice have complete
deficiency of plasma phospholipid transfer activity and markedly reduced high density …
are homologous molecules that mediate neutral lipid and phospholipid exchange between
plasma lipoproteins. Biochemical experiments suggest that only CETP can transfer neutral
lipids but that there could be overlap in the ability of PLTP and CETP to transfer or exchange
phospholipids. Recently developed PLTP gene knock-out (PLTP0) mice have complete
deficiency of plasma phospholipid transfer activity and markedly reduced high density …