[HTML][HTML] Role of adult bone marrow stem cells in the repair of ischemic myocardium: current state of the art
S Charwat, M Gyöngyösi, I Lang, S Graf, G Beran… - Experimental …, 2008 - Elsevier
OBJECTIVE: To review the milestones in stem cell therapy for ischemic heart disease from
early basic science to large clinical studies and new therapeutic approaches. MATERIALS
AND METHODS: Basic research and clinical trials (systematic review) were used. The heart
has the ability to regenerate through activation of resident cardiac stem cells or through
recruitment of a stem cell population from other tissues, such as bone marrow. Although the
underlying mechanism is yet to be made clear, numerous studies in animals have …
early basic science to large clinical studies and new therapeutic approaches. MATERIALS
AND METHODS: Basic research and clinical trials (systematic review) were used. The heart
has the ability to regenerate through activation of resident cardiac stem cells or through
recruitment of a stem cell population from other tissues, such as bone marrow. Although the
underlying mechanism is yet to be made clear, numerous studies in animals have …