Structural biology of hepatitis C virus
F Penin - Clinics in liver disease, 2003 - liver.theclinics.com
Hepatitis C virus (HCV) is a small-enveloped RNA virus estimated to infect roughly 170
million people worldwide [1]. HCV is remarkably efficient at establishing and maintaining
chronic infection and evolving mechanisms to evade the host responses. The insidious
course of the disease and the poor prognosis for long-term persistent infection lead to
severe liver diseases (steatosis, liver cirrhosis, and hepatocellular carcinoma), constituting
the main cause of liver transplantation, and making this pathogen a serious medical and …
million people worldwide [1]. HCV is remarkably efficient at establishing and maintaining
chronic infection and evolving mechanisms to evade the host responses. The insidious
course of the disease and the poor prognosis for long-term persistent infection lead to
severe liver diseases (steatosis, liver cirrhosis, and hepatocellular carcinoma), constituting
the main cause of liver transplantation, and making this pathogen a serious medical and …
