Bronchial biopsy findings in intermittent or" early" asthma

LA Laitinen, A Laitinen, A Altraja, I Virtanen… - Journal of allergy and …, 1996 - Elsevier
Bronchial biopsy specimens from subjects with intermittent or" early" asthma were compared
with specimens taken from healthy subjects. Patients with early asthma included those with
seasonal asthma and occupational asthma. There was a small but statistically significant
increase in the thickness of the subepithelial extracellular matrix protein tenascin in subjects
with seasonal and occupational asthma compared with control subjects. Collagen types IV
and VII were increased only in patients with occupational asthma. Eosinophils were the only …