Elevated cerebrospinal fluid and serum nitrate and nitrite levels in patients with central nervous system complications of HIV-1 infection: a correlation with blood-brain …
As nitric oxide (⋅ NO) is hypothesised to play a role in the immunopathogenesis of
neurological complications associated with inflammation, we compared levels of
cerebrospinal fluid (CSF) and serum⋅ NO metabolites in 24 patients with HIV-1 infection, to
those in 58 non-HIV infected patients with neurological disorders. Levels of⋅ NO
metabolites were correlated with blood-brain-barrier dysfunction. CSF and serum nitrate and
nitrite levels were measured by the nitrate reductase and Griess reaction methods. The⋅ NO …
neurological complications associated with inflammation, we compared levels of
cerebrospinal fluid (CSF) and serum⋅ NO metabolites in 24 patients with HIV-1 infection, to
those in 58 non-HIV infected patients with neurological disorders. Levels of⋅ NO
metabolites were correlated with blood-brain-barrier dysfunction. CSF and serum nitrate and
nitrite levels were measured by the nitrate reductase and Griess reaction methods. The⋅ NO …
